Tag Archive: cocaine


Three policemen, with difficulty, drag an agitated and very combative young man into an emergency room. Once there, he is restrained because he reacts with rage and tries to hit anyone who approaches him. When it is finally safe to approach him, the resident on call notices that the patient has very prominent vertical nystagmus. Shortly thereafter, the patient has a generalized seizure. Which of the following substances of abuse is the most likely to produce this presentation?

a. Amphetamine

b. PCP

c. Cocaine

d. Meperidine

e. LSD

the answer is below…

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A 20-year-old man is admitted to the emergency department after an automobile accident, in which his friend drove their car into a light pole. In the emergency department, the man smells strongly of alcohol, and his blood alcohol level is 300 mg/dL. However, he does not show any typical signs of intoxication. His gait is steady, his speech is clear, and he does not appear emotionally disinhibited. Which of the following is the most likely explanation for such a presentation?

a. The adrenaline generated in the patient because of the effects of the car crash has counteracted the alcohol in his system

b. A value of 300 mg/dL is below the intoxication level

c. The man has developed a tolerance to the effects of alcohol

d. There has been a laboratory error

e. The man has recently used cocaine, whose effects counteract the effects of alcohol intoxication

the answer is below…

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Saya kutip artikel kesehatan ini dari Medscape.

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Top Medical News Stories of 2011

Laird Harrison

November 28, 2011 — Concerns about simvastatin, linezolid, methylene blue dye, and “bath salts” all made headlines during 2011. The possibility of cancer from cell phones came into the spotlight as well.

That’s not to say that the news was all bad. The US Food and Drug Administration (FDA) approved a new drug for diabetes, linagliptin.

1. FDA Calls for Simvastatin Limits

The FDA played a role in most of this year’s top news stories, starting with a June 8 recommendation that physicians restrict prescribing high doses of the cholesterol medication simvastatin (Zocor, Merck) because of a risk for muscle damage. The FDA drug safety communication states that physicians should limit using the 80-mg dose of simvastatin unless the patient has already been taking the drug for 12 months and there is no evidence of myopathy.

In addition, the FDA required that the label include the new dosing recommendations, as well as warnings not to use the drug with various medications, including itraconazole (Sporanox, Janssen Pharmaceuticals), ketoconazole (Nizoral, Ortho-McNeil Pharmaceutical), posaconazole (Noxafil, Merck), erythromycin, clarithromycin, telithromycin (Ketek, sanofi-aventis), HIV protease inhibitors, nefazodone, gemfibrozil, cyclosporine, and danazol.

In addition, the 10-mg dose should not be exceeded in patients taking amiodarone, verapamil, and diltiazem, and the 20-mg dose should not be exceeded when taken with amlodipine (Norvasc, Pfizer) and ranolazine (Ranexa, Gilead).

2. FDA Warns of Methylene Blue and Linezolid Serotonin Interactions

Then, on July 26, the FDA warned against the use of methylene blue or linezolid with serotonergic drugs. In particular, the FDA said in an October 21 update that clinicians should watch out for interactions with serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors. Continue reading

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