A 29 year-old woman with a history of malignant melanoma presents to her primary care doctor with a new type of headache. Examination is normal and a head CT is ordered. Multiple small brain hemorrhages are revealed by the scan. Metastatic lesions to the brain most often appear in which of the following locations?

a. At the gray-white junction

b. In the thalamus

c. In the posterior fossa

d. In the caudate

e. In the sella turcica

the answer is below…

The United States Medical Licensing Examination, or USMLE for short, is a three-part licensing examination that is required in order to receive a license to practice medicine within the United States.

The USMLE assesses a physician’s ability to apply knowledge, concepts, and principles, and to determine fundamental patient-centered skills that are important in health and disease and that constitute the basis of safe and effective patient care.Examination committees composed of medical educators and clinicians from across the United States and its territories prepare the examination materials each year.

This exam is designed by the Federation of State Medical Boards and the National Board of Medical Examiners to determine whether or not an individual understands and can apply the knowledge necessary to practice medicine safely and intelligently.

The USMLE is actually comprised of three different exams that are referred to as steps, which examine the individual’s knowledge of specific topics related to the field of medicine such as basic science, medical knowledge, medical skills, clinical science, and the application of all of these skills and areas of knowledge in the medical field.

All three steps of the USMLE include a series of computerized multiple-choice questions, but the format of the exam and the information covered in each multiple-choice section is different for each step of the USMLE. The USMLE Step II also has a clinical skills portion that examines an individual’s ability to work with real patients and the USMLE Step III has a computerized patient simulation portion in addition to the multiple-choice section of the exam. In order for an individual to receive a license to practice medicine, the individual must pass all three steps of the USMLE.

Medical doctors with an M.D. degree are required to pass this examination before being permitted to practice medicine in the United States of America

The correct answer is a; At the gray-white junction.[2]

Metastatic lesions are spread primarily by the vascular system. The gray-white junction (where the white matter and the gray matter meet) is the interface at which bloodborne cells are most likely to lodge and grow. No part of the brain is exempt from the spread of metastases, but the cerebral hemispheres and the cerebellum are especially vulnerable.